The GEnomics of MusculoSkeletal traits TranslatiOnal Network (GEMSTONE) COST Action, is a European research network funded by COST Association. This network fosters collaboration among experts
Bone: A rigid body tissue that makes up our body’s skeleton.
Craft: Skill and experience
BoneCraft.nl describes the expertise and experience of the Bone, Imaging & Genomics (BIG) research group of the Department of Internal Medicine at Erasmus MC. Our group is committed to transforming BIG research discoveries into tangible clinical solutions for individuals vulnerable to (musculo)skeletal disorders and other complex diseases.
Lines of research
The research of the BIG group is organized along four lines, with the first three defining the team organization (on expertise and trajectory); while the fourth line represents the clinical translation arm of the BIG group, implementing discoveries generated by the other research lines in the form of health benefit for the general population and improved patient care.
Bone Biology & Mechanistic Research
Our research aims at elucidating the cellular, molecular, and physiological mechanisms underlying the regulation of bone development, remodelling, adaptation, repair and disease.
Population Musculoskeletal Genomics, Imaging and Life-Course Epidemiology
We aim at identifying genetic, molecular, environmental, and lifestyle determinants of musculoskeletal traits and diseases throughout life using population-based cohorts and high-throughput genomic and imaging technologies.
Rare and Atypical Skeletal Disorders
Our research aims at improving the understanding, diagnosis, and management of rare skeletal diseases and atypical presentations of common (musculo)skeletal disorders.
Clinical Phenomics and Precision Skeletal Medicine
We integrate clinical phenotyping, imaging, genomics, and molecular profiling to transform how we diagnose, predict, and treat musculoskeletal diseases. By applying machine learning to population and patient big data, we bridge biology, genetics, environment, and lifestyle—paving the way for advanced fracture risk prediction, targeted prevention, and personalized health outcomes.
Projects
Featured Staff
Tarsila de Moura Figueiredo
PhD Researcher
I am Tarsila de Moura Figueiredo. I obtained my diploma in Dentistry from the University of Brasília, Brazil, and specialized in Periodontology at the University of São Paulo, Brazil. Currently, I am finishing a Master’s degree in Health Sciences, Major in Genetic and Molecular Epidemiology, at Erasmus MC, the Netherlands. In September 2023 I started working as a PhD at the Department of Oral and Maxillofacial Surgery at Erasmus MC.
- Favorite
My hobby is playing the flute. I played in the military band of my school in Brazil for most of my childhood. After university, I have been too busy to play it regularly. But, I still enjoy playing it. I also enjoy watercolor and doing crafts, such as macramé.
Partners
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