GEFOS

The GEFOS study is a project aimed at identifying genetic determinants of musculoskeletal and aging-related traits. It focuses on genetic risk factors for osteoporosis, novel bone phenotypes, and gene-environment interactions, and translating findings into clinical practice. Since 2008, GEFOS has made numerous genomic discoveries in bone and muscle phenotypes, including BMD, lean mass, and grip strength, through large-scale GWAS meta-analyses.