The Erasmus MC Transplant Institute has been a pioneer in kidney transplantation for 50 years, specializing in living donor transplants. It serves as a national referral center for complex cases, including highly immunized patients, with the CIAT program. The institute offers a range of transplant options, such as cross-over and domino donations, as well as advancements across blood groups and immunological barriers. Supported by state-of-the-art laboratories and comprehensive psychosocial expertise, the institute is the largest in the Netherlands for liver, kidney, lung, and heart transplants, catering to both adults and children.