Laboratory for Calcium and Bone Metabolism

The Laboratory for Calcium and Bone Metabolism is dedicated to advancing the understanding of skeletal disorders and discovering new treatments for bone and mineral imbalances. Our research focuses on key areas such as bone regeneration, the complex interactions in bone metastases, and rare bone diseases. By utilizing advanced models and techniques, we aim to uncover the mechanisms behind these conditions and identify novel therapeutic targets.

Our research includes investigating the processes of bone cell differentiation and the factors that regulate bone formation and degradation. We explore diseases like osteoporosis, craniosynostosis, and improve fracture healing through a variety of molecular, cellular, and technical approaches. Additionally, we study the interactions between bone metastatic cancer cells and osteoblasts to develop new therapeutic strategies for bone metastases.

The Laboratory also focus on rare, monogenic disorders that affect bone and mineral metabolism. By combining molecular, cellular, and animal studies, we aim to understand the genetic factors involved and apply findings from individual patients and population cohorts to advance treatments. Overall, our goal is to deepen our understanding of skeletal diseases and find innovative ways to treat disturbances in bone and mineral homeostasis.