Deliverables
Deliverable 1
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WP5
Work package 5 Translating Genomic and Imaging Insights into Clinical Practice for Improved Bone Health All work packages Integrated genomic profiling and Imaging clustering of patients (clinical setting): The objective of this work package is to translate genomic discoveries and imaging insights on skeletal fragility into clinical practice, with the aim of improving patient care. […]
WP4
Work package 4 Revolutionizing Bone Disease Diagnosis with AI-Deep Learning Artificial intelligence-deep learning: The objective of this work package is to employ artificial intelligence-deep learning (AI-DL) approaches to revolutionize current clinical approaches to bone disease. In recent years, artificial intelligence, particularly deep learning (DL) and convolutional neural networks (CNN), has made significant strides in the […]
WP3
Work package 3 Enhancing Bone Quality Assessment: Integrating RPI Technology in Skeletal Research Large-scale assessment of bone quality (Osteoprobe): The objective of this work package is to advance beyond traditional bone mineral density (BMD) measurements and assess bone quality as a determinant of bone fragility and fracture risk, as well as the potential detrimental effects […]
WP2
Mv. Birgit Doorn, ERGO deelnemer wordt gescand Work package 2 Revolutionizing Skeletal Research with Large-Scale EOS 3D X-Ray Imaging Large-scale EOS 3D X-ray imaging: The objective of this work package is to establish a comprehensive collection of innovative skeletal imaging assessments to advance research on skeletal fragility. To accomplish this, we will acquire an EOS® […]
Work Packages
LEGENDARE is a European Research Council (ERC) funded research project aimed at advancing our understanding of human skeletal fragility and associated conditions through innovative genomic approaches. The project is structured into five distinct work packages (WP’s), each focusing on a different area of expertise to comprehensively address the challenges of bone health and fragility.
WP1
Work package 1 Refining Genomic Profiles for Improved Insights into Skeletal Diseases Integrated genomic profiling and Imaging clustering of patients (clinical setting): The objective of this work package is to translate genomic discoveries and imaging insights on skeletal fragility into clinical practice, with the aim of improving patient care. Genomic studies provide a wealth of […]
Gemstone
The GEnomics of MusculoSkeletal traits TranslatiOnal Network (GEMSTONE) COST Action, is a European research network funded by COST Association. This network fosters collaboration among experts in genetics, epidemiology, bioinformatics, and clinical medicine across Europe, to enhance the translation of genomic discoveries in the musculoskeletal field, into clinical applications. Participants include researchers and clinicians from various academic and medical institutions, chosen for their relevant expertise.
SNP Course 2024
Join the 2024 SNP Course at Erasmus MC – Unlock the Power of Genetic Variants!
Discover the latest advancements in Single Nucleotide Polymorphism (SNP) analysis at the Erasmus MC SNP Course 2024. This intensive program covers cutting-edge methodologies, bioinformatics tools, and real-world applications in genetics research. Learn from renowned experts and gain hands-on experience in SNP data analysis.