Work Packages
LEGENDARE is a European Research Council (ERC) funded research project aimed at advancing our understanding of human skeletal fragility and associated conditions through innovative genomic approaches. The project is structured into five distinct work packages (WP’s), each focusing on a different area of expertise to comprehensively address the challenges of bone health and fragility.
WP1
Work package 1 Refining Genomic Profiles for Improved Insights into Skeletal Diseases Integrated genomic profiling and Imaging clustering of patients (clinical setting): The objective of this work package is to translate genomic discoveries and imaging insights on skeletal fragility into clinical practice, with the aim of improving patient care. Genomic studies provide a wealth of […]
Gemstone
The GEnomics of MusculoSkeletal traits TranslatiOnal Network (GEMSTONE) COST Action, is a European research network funded by COST Association. This network fosters collaboration among experts in genetics, epidemiology, bioinformatics, and clinical medicine across Europe, to enhance the translation of genomic discoveries in the musculoskeletal field, into clinical applications. Participants include researchers and clinicians from various academic and medical institutions, chosen for their relevant expertise.
SNP Course 2024
Join the 2024 SNP Course at Erasmus MC – Unlock the Power of Genetic Variants!
Discover the latest advancements in Single Nucleotide Polymorphism (SNP) analysis at the Erasmus MC SNP Course 2024. This intensive program covers cutting-edge methodologies, bioinformatics tools, and real-world applications in genetics research. Learn from renowned experts and gain hands-on experience in SNP data analysis.
Fidelio
FIDELIO, funded by Horizon 2020, trained researchers on bone fragility in type 2 diabetes, focusing on genetic mechanisms and biomarkers for improved detection and treatment of diabetes-induced osteoporosis.
Legendare HOME
LEGENDARE is a program funded by the ERC Advanced Grant No.20800 500 aimed at using genomics for preventing and managing human skeletal fragility and associated conditions.
Sinter – HOME
The SINTER Study examines bone strength, influenced by genetics, aging, and lifestyle. Osteoporosis, linked to low bone mass and high fracture risk, worsens with age and health conditions like diabetes
Wetenschappers ontdekken 12.111 gebieden in het DNA die lichaamslengte bepalen
Onderzoekers van Erasmus MC identificeerden 12.111 genoomgebieden die 40-50% van de lengteverschillen in Europese populaties verklaren. Deze doorbraak biedt nieuwe inzichten in genetica, groeistoornissen en aandoeningen zoals osteoporose en obesitas. De resultaten zijn gepubliceerd in Nature.
ERC Advanced Grant voor osteoporose-onderzoek
Prof. Dr. Fernando Rivadeneira ontvangt een ERC Advanced Grant voor onderzoek naar osteoporose. Met AI-technieken combineert hij genetica, beeldvorming en botkwaliteitmetingen om oorzaken en diagnostiek te verbeteren.