Aim: To integrate deep clinical phenotyping, imaging, genomics, and molecular profiling to improve diagnosis, prognosis, and treatment of patients with musculoskeletal diseases.

Key activities

• Assembly of clinical cohorts (SINTER, Phosphate)
• Seel phenotyping harmonization across outpatient clinics
• Skeletal fragility associated with chronic diseases
• Patient stratification and outcome prediction
• Precision medicine implementation

Scientific question

• How can integrated phenotyping improve clinical care and outcomes for musculoskeletal patients?